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. They discovered which the focus of HBsAg secreted within the mobile culture and mouse serum was diminished by CRISPR/Cas9 procedure. They concluded that a CRISPR/Cas9 technique inhibited HBV replication and expression in vitro As well as in vivoSulfhydryl alkylating agent that inactivates NADP-dependent isocitrate dehydrogenase and many endonucle